Question

Preventing heart attacks: Medical researchers performed a comparison of two drugs, clopidogrel and ticagrelor, which are designed to reduce the risk of heart attack or stroke in coronary patients. A total of 6688 patients were given clopidogrel, and 6746 were given ticagrelor. Of the clopidogrel patients, 675 suffered a heart attack or stroke within one year, and of the ticagrelor patients, 553 suffered a heart attack or stroke. Can you conclude that the proportion of patients suffering a heart attack or stroke is less for ticagrelor? Let p1 denote the proportion of patients suffering a heart attack or stroke with clopidogrel and p2 denote the proportion of patients suffering a heart attack or stroke with ticagrelor. Use the =α0.01 level of significance and the critical value method.

State the null and alternate hypotheses

Choose a significance level and find the critical value(s)

Compute the test statistic.

Determine whether to reject H0.

State a conclusion at the α=0.01 level of significance.

Answer 1