Question

Researchers at an abdominal transplant clinic are concerned about the rates of kidney graft failure reported...

Researchers at an abdominal transplant clinic are concerned about the rates of kidney graft failure reported by patients based on the gender discordance between host and donor. Gender discordance in transplant is when the host receives a kidney from a donor of the opposite gender. Suppose the following table reports the outcome of a preliminary analysis on the rates of graft failure with either gender discordance or no gender discordance.

Graft Failure

No Graft Failure

Total

Gender Discordance

32

35

67

Gender Concordance

21

116

137

Total

53

151

204


A) Calculate the incidence of graft failure for both exposed and nonexposed.

B) Carry out a formal test of significance to determine if there is a difference in graft loss based on gender discordance.

C) Calculate the relative risk for graft failure based on gender discordance.

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