- A serum cholesterol level above 250 mg/dl of blood is a risk
factor for cardiovascular disease in humans. At a
medical center in St. Louis, a study to test the effectiveness of
new cholesterol-lowering drug was conducted. One hundred
people with cholesterol levels between 250 mg/dl and 300 mg/dl were
available for this study. Fifty people were assigned at
random to each of two treatment groups. One group
received the standard cholesterol-lowering medication and the other
group received the new drug. After taking the drug for
three weeks, the 50 subjects who received the standard treatment
had a mean decrease in cholesterol level of 10 mg/dl with a
standard deviation of 8 mg/dl and the 50 subjects who received the
new drug had a mean decrease of 18 mg/dl with a standard deviation
of 12 mg/dl.
Does the new drug appear to be more effective than the standard
treatment in lowering mean cholesterol level?
- Write the null and alternative hypotheses to test this
claim.
- Perform a two sample t-test for the difference of two
mean. What is the value of the test statistic?
- What is the associated P-Value?
- State your conclusion using .
- Create a 95% confidence interval for the true mean difference
in effectiveness of treatment.