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In a prospective cohort study of exposure to asbestos and mesothelioma with a total of 350...

  1. In a prospective cohort study of exposure to asbestos and mesothelioma with a total of 350 study participants, 170 study participants were exposed to asbestos. By the end date of the study, 97 participants had developed mesothelioma including 20 not exposed to asbestos.
    1. Set up the 2x2 table below. Label all elements and complete the table with the correct numbers.
    1. What measure of association should you calculate?

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Answer #1
A(asbestos) a(not asbestos)
B(mesothelioma) (AB)=77 (aB)=20
b(not mesothelioma) (Ab)=93 (ab)=160

(a)Since we have

(b) we can use Yules coefficient of association which is given by

So attribute A,B are independent if Q=0, if Q=1 then A,B are completely associated on the other hand if Q=-1 then complete dissociation so so here we have Q =0.7376 which means high degree of positive association between two attribute A,B

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