In a test of the effectiveness of garlic for lowering cholesterol, 4747 subjects were treated with garlic in a processed tablet form. Cholesterol levels were measured before and after the treatment. The changes (beforeminus−after) in their levels of LDL cholesterol (in mg/dL) have a mean of 5.3 and a standard deviation of 19.7. Construct a 95% confidence interval estimate of the mean net change in LDL cholesterol after the garlic treatment. What does the confidence interval suggest about the effectiveness of garlic in reducing LDL cholesterol?
Answer)
As the population s.d is unknown here we will use t distribution table to construct the interval
Given info
Mean = 5.3
S.d = 19.7
N = 47
Confidence level = 95%
Degrees of freedom is = n-1 = 46
For 46 dof and 95% confidence level
Critical value t is = 2.01
Margin of error (MOE) = t*s.d/√n = 2.01*19.7/√47 = 5.784
Interval is given by
(Mean - MOE, Mean + MOE)
[-0.484, 11.084].
We are 95% confident that the population mean difference falls between -0.484 and 11.084.
Null hypothesis Ho : u1 - u2 = 0
Alternate hypothesis Ha : u1-u2 not equal to 0
So as the interval contains the null hypothesised value 0 in it
We fail to reject the null hypothesis Ho
So do not have enough evidence to conclude that garlic is effective in reducing LDL
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