Question

The paper “Effect of long-term blood pressure control on salt sensitivity” [Journal of Medicine (1997) 28:147–156] describes a study evaluating salt sensitivity (SENS) after a period of antihypertensive treatment. Ten hypertensive patients (diastolic blood pressure between 90 and 115 mmHg) were studied after at least 18 months on antihypertensive treatment. SENS readings, which were obtained before and after the patients were placed on an antihypertensive treatment, are given in table.

a) Write the null and alternate hypotheses

b) mention the name of the test and also all assumptions required. test the assumptions

c) compute the p-value (or critical value) and include any relevant code

d) Is there significant evidence that the mean SENS value decreased after the patient received antihypertensive treatment?

'Before'	'After'
22.86	6.11
7.74	-4.02
15.49	8.04
9.97	3.29
1.44	-0.77
9.39	6.99
11.4	10.19
1.86	2.09
-6.71	11.4
6.42	10.7

Answer 1