Question

3. A combination drug has two components. A. the antihistamine and B the decongestant. A clinical trial is designed in two parts: part 1 to randomly assign patients to either a placebo control or drug A, and part II to randomly assign a second group of patients to a placebo control or drug B. A more efficient plan is to use a design with a (1 mark)

1. 2 stage cluster sampling
2. Systematic random sample
3. Good compliance history
4. Random allocation of adverse drug experiences
5. Factorial arrangement of treatment

Answer 1

Problem statement: Suggest an experiment design to study the effect of combination drug other than mentioned in the question.

Solution: correct answer choice is (e).

Explanation: Since the problem statement requires us to suggest an experiment design to study the effect of drugs A and B in a combinational drug efficiently we have to opt for Factorial arrangement of treatment. Factorial arrangement is an experimental design technique where effects of different factors on subjects can be studied at one. Thus we opt answer choice (e).