Question

Suppose we want to design a new study to assess the implications of childhood obesity on...

Suppose we want to design a new study to assess the implications of childhood obesity on poor health outcomes in adulthood. In the study we will consider total cholesterol at age 50 and incident cardiovascular disease by age 50 as the key outcomes. We will compare normal versus overweight/obese children. Assume that the standard deviation in total cholesterol is 35.

a. How many normal and overweight/obese children are required to ensure that a 95% confidence interval estimate for the difference in total cholesterol has a margin of error not exceeding 5 units?

b. How many normal and overweight/obese children are required to ensure 80% power to detect a 4% difference in incident cardiovascular disease between groups? Assume that approximately 3% of normal weight children will develop cardiovascular disease by age 50 and that 7% of overweight/obese children will develop cardiovascular disease by age 50 and that a two sided test with =0.05 will be used.

c. How many normal and overweight/obese children should be enrolled to satisfy (a) and (b) assuming that 20% will be lost to follow-up over the course of the study?

Homework Answers

Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
What is the appropriate statistical test to assess whether there is an association between obesity status...
What is the appropriate statistical test to assess whether there is an association between obesity status (normal weight, overweight, obese) and 5-year incident cardiovascular disease (CVd.? Suppose each participant’s obesity status (category) is known along with whether they develop CVD over the next 5 years or not.
18. What is the appropriate statistical test to assess whether there is an association between obesity...
18. What is the appropriate statistical test to assess whether there is an association between obesity status (normal weight, overweight, obese) and 5-year incident cardiovascular disease (CVD)? Suppose each participant’s obesity status (category) is known along with whether they develop CVD over the next 5 years or not
We wish to design a longitudinal study to assess risk factors for stroke. One primary outcome...
We wish to design a longitudinal study to assess risk factors for stroke. One primary outcome of the study is incident of stroke. In patients over the age of 65, approximately 14% develop stroke over 25 years. How many participants over the age of 65 must be enrolled to ensure the following? That we have 80% power to detect a 25% reduction in incidence of stroke between participants who participate in a healthy aging program as compared to those who...
Suppose we want to do a study on the body mass index (BMI) on patients who...
Suppose we want to do a study on the body mass index (BMI) on patients who are free of diabetes and participating in a study of risk factors for obesity. Body mass index is measured as the ratio of weight in kilograms to height in meters squared. 1. How many participants would be needed to ensure that a 95% confidence interval estimate of BMI had a margin of error not exceeding 2 units? Assume that the standard deviation of BMI...
Q: Write Two PES statement for the following short case study. JJ is a 50 y.o....
Q: Write Two PES statement for the following short case study. JJ is a 50 y.o. woman who works as an accountant. She presents to her family physician with elevated blood pressure and obesity. JJ has struggled with her weight since childhood and indicates that her weight problems worsened 5 years ago when she returned to work as an accountant. Nutrition Assessment Client History: Age- 50 years old Gender- Female Married with three children-ages 20, 15, and 10 Medical/Health History-...
A researcher is concerned that his new antihypertensive medication may be causing insomnia in some of...
A researcher is concerned that his new antihypertensive medication may be causing insomnia in some of his patients. Suppose he gathers a SRS of 65 patients treated with the study drug with a sample average of 6.6 hours of sleep and a σ=1.1. Assuming that insomnia can be quantified as an average of 4.5 hours of sleep, can we determine with 95% confidence that his drug avoids diagnosis of insomnia as a side-effect?                Ho: µ=4.5, Ha: µ<4.5 Z stat=12.4...
Question 6 An investigator is looking at the relationship between periodontal disease and the onset of...
Question 6 An investigator is looking at the relationship between periodontal disease and the onset of hypertension. Suppose the investigator decides to look at height as a variable that may confound the relationship between exposure and case status in his study. After collecting information about the height of each participant, he assembles a database that approximates height with the normal distribution. A) Assuming the mean of the distribution is 176.2 cm with a standard deviation of 17.5 cm, what are...
Objective: The student will apply course objectives through evaluating patient assessments, identifying treatment options and developing...
Objective: The student will apply course objectives through evaluating patient assessments, identifying treatment options and developing teaching plans for patients with obesity, peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). Part I: Obesity & Bariatric Surgery A 32-year-old obese patient has come to the bariatric outpatient center to have an initial evaluation. The patient reports that they were always overweight, even as a child. The patient states that they are frustrated because they gained 100 pounds over the last...
Pfizer was established in 1849 in Brooklyn, New York by cousins Charles Pfizer and Charles Erhart...
Pfizer was established in 1849 in Brooklyn, New York by cousins Charles Pfizer and Charles Erhart with a loan of $2,500 from Pfizer’s father.2 Today, 167 years later, Pfizer Inc. has international revenues of $49 billion, which makes it the second-largest pharmaceutical manufacturer in the world.3 Despite Pfizer’s success, the company has faced many challenges over the last few decades. The pharmaceutical industry is heavily influenced by legal, political, and technological forces, and all indications are that the industry will...
In narrative essay format, I want you to address a business/organization case study using multiple concepts...
In narrative essay format, I want you to address a business/organization case study using multiple concepts from class. The case question and case text begin on page 5 of this document. You need to demonstrate their best understanding of management and organizational behavior theory, and the application of those ideas to improve the understanding of various issues. You need to clearly identify at least 3 distinct, substantive issues. For each issue you need to 1), identify evidence from the case...
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT