A 1980 study investigated the relationship between the use of OCs and the development of endometrial cancer. The researchers found that of 117 endometrial-cancer patients, 6 had used the OC Oracon at some time in their lives, whereas 8 of the 395 controls had used this agent. With this information, calculate an odds ratio and a 95% Confidence Interval. Then interpret the ratio with the 95% confidence interval.
Used OC Oracon | Didn't used OC Oracon | Total | |
Endometrial cancer patients | 6 | 111 | 117 |
Controls | 8 | 387 | 395 |
Total | 14 | 498 | 512 |
Odds ratio=
The formula for the 95% Confidence Interval for the odds ratio is as follows:
The standard error for log(OR) is computed using the following equation:
=
95% CI=
=
In this study, subjects using OC ocaron are 2.614 times the odds of developing Endometrial cancer compared to non-user subjects. With 95% confidence, the true odds ratio lies in the range of (0.888,7.699)
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