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The drug ancrod was tested in a double-blinded clinical trial in which subjects who had strokes...

The drug ancrod was tested in a double-blinded clinical trial in which subjects who had strokes were randomly assigned to get either ancrod or a placebo. One outcome of interest in the study was whether or not a subject experienced intracranial hemorrhaging. In the ancrod group 13 of 248 experienced hemorrhaging, compared to 6 patients out of 252 in the placebo group.

a. Compute a 90% confidence interval for the difference of the proportions of patients experiencing hemorrhaging in the two groups.

b. Conduct an appropriate test to determine whether the proportions of patients experiencing hemorrhaging in the two groups are different. Use a significance level of 0.05.

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