Question

The next tables show the data when patients are broken into subgroups based on the L-indicator...

  1. The next tables show the data when patients are broken into subgroups based on the L-indicator counts.

Table 2: HIGH L-indicator counts

Response

No Response

Treatment A

20

110

Treatment B

5

30

Table 3: REGULAR L-indicator counts

Response

No Response

Treatment A

25

10

Treatment B

90

40

  1. Show that Treatment A has a better response rate in each of the two L-indicator categories.

  1. What is the overall response rate (pooled proportion) among patients with regular L-indicator counts?

  1. What is the overall response rate among patients with high L-indicator counts?
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Answer #1

For High L-indicator

The response rate of Treatment A =

The response rate of Treatment B =

For Regular L-indicator

The response rate of Treatment A =

The response rate of Treatment B =

So, in every cases Treatment A has a better response rate in both the cases as 0.15 > 0.14 and 0.71 > 0.69

Now, the overall response rate (pooled proportion) among regular L-indicator =

Now, the overall response rate (pooled proportion) among high L-indicator =

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