Question

Mark et at. (A-31) conducted a study to determine the effects of rapid weight loss on gallbladder contraction and assess the effects of ursodiol and ibuprofen on saturation, nucleation and growth, and contraction. The individuals studied were obese patients randomly distributed to receive urdisol, ibuprofen or placebo. Among the data collected are the following data corresponding to cholesterol saturation indices (ISC) and nucleation times (TN) in individuals treated with placebo for 13 days (6 men, 7 women) at the end of six weeks.

ISC	TN
1.20	4.00
1.42	6.00
1.18	14.00
.88	21.00
1.05	21.00
1.00	18.00
1.39	6.00
1.31	10.00
1.17	9.00
1.36	14.00
1.06	21.00
1.30	8.00
1.71	2.00

a) Apply a statistical analysis of the data (which includes hypothesis testing and elaboration

of confidence intervals) that can produce useful information for researchers.

b) Create graphs that may be useful to illustrate the relationships between the variables.

c) Where appropriate, use techniques such as analysis of variance, hypothesis testing and estimation of intervals with respect to means and proportions.

d) Determine the p-values for each statistical test.

e) Establish all the necessary assumptions to validate the analysis.

f) Describe the population (or populations) on which the inferences could be applied based on the analysis performed.

g) If possible, consult the references cited and compare the results of the analyzes against the results presented by the author.

Answer 1