A screening test for a rare form of TB has a 7% false positive
rate (i.e.
indicates the presence of the disease in people who do not have
it). The
test has an 8% false negative rate (i.e. indicates the absence of
the disease
in people who do have it). In a population of which 0.6% have the
disease,
what is the probability that someone who tests positive has the
disease?
ANSWER:
(i) Probability of having disease, P(B1) = 0.006.
Probability of not having disease, P(B2) = 1 - P(B1)
P(B2) = 1 - 0.006
= 0.994.
(ii) P(testing positive | having disease), P(A | B1) = 1 - P(false negative)
= 1 - 0.08
= 0.92
P(testing positive | not having disease), P(A | B2) = P(false positive) = 0.07
P(A) = P(A B1) + P(A B2) = P(A | B1) x P(B1) + P(A | B2) x P(B2)
=( 0.92 x 0.006 )+ (0.07 x 0.994 )
= (0.00552+0.06958)
=0.0751.
(iii) P(has disease | tests positive),
P(B1 | A)
=P(A B1) / P(A)
=(0.92*0.006)/(0.0751)
=0.0735
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