Question

# Hypothesis Test: In a blinded crossover trial, a diet of almonds and its effect on LDL-C,...

Hypothesis Test:

In a blinded crossover trial, a diet of almonds and its effect on LDL-C, a group with elevated LDL-C underwent diet of increased almond intake. LDL-C measured before and after almond diet. The following LDL-C measurements were made on the 11 subjects (mg/dL):

Subject #1: pre-almond- 140, post- 143

2: 159, 136      3: 157, 130

4: 152, 142

5: 155, 131

6: 152, 144

7: 158, 116

8: 155, 136

9: 146, 130

10: 153, 125

11: 141, 138

Is there a significant mean difference between their LDL-C pre-almond and post-almond diet? Use the p-value method.

H0: There is no significance difference between the means of the LDL-C Pre-almond and Post-almond diet

H1: There is significance difference between the means of the LDL-C Pre-almond and Post-almond diet

Let the los be alpha = 5%

From the given data

 Pre-almond post Difference 140 143 -3 159 136 23 157 130 27 152 142 10 155 131 24 152 144 8 158 116 42 155 136 19 146 130 16 153 125 28 141 138 3

P-Value: 0.0010

Since P-value < alpha 0.05 so we reject H0

Thus we conclude that there is significance difference between the means of the LDL-C Pre-almond and Post-almond diet