A tracer study drug contains 10 kBq of 99mTc which has a half-life of 363 minutes. Technetium can be used as a substitute for 131I in tracer studies of the thyroid gland. What is the activity of the drug 3 hours after it was administered?
Let the initial activity of the mTc is A0 = 10 k Bq = 104 Bq
Half life of the sample is T1/2 = 363 min = 21780 s
Disintegration constant = 0.693 / T1/2
Time after which activity needs to be calculated t = 3 hours
Time t = 10,800 s
Activity of a simple after a time t is given by
A = A0 e-t
= A0 * { e-t * (0.693 / T1/2) }
= 104 * { e-(10800 * 0.693 / 21780 ) }
= 104 * e-0.3436
= 104 * 0.709
= 7.09 * 103 Bq
= 7.09 k Bq
So the activity reduces to 7.09 kBq in 3 hours
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