18F (half-life of 110 min) is produced at a rate of 1 Ci/hr per one gram of solution.
1, Calculate the activity (in Ci) resulting after irradiating 10 grams of solution for one hour.
2, Calculate the activity (in Ci) resulting for an irradiation of 2 gm solution for 5 hours
3, Calculate the activity (in Ci) resulting for an irradiation of 1 gm solution for 10 hours
Ao is the rate of production of the activiity
is the decay const ( = 0.693/T1/2 )
at any instant of time Ao nuclie are produced, and if there are N(t) nuclie present,
out of this N(t) would decay
the rate of change of nuclie is given by
dN(t)/dt = Ao - N(t)
intially the activity is 0 integrating the above from 0 to t
the activity of the isotope at any time is given by
N(t) = Ao {1- exp(-t) }
= 0.693/ T1/2 = 0.693/110 = 0.0063 m-1 = 1.05e-4 hr-1
production rate Ao = 1Ci/hr/gm
1. 10 gms solution Ao = 10Ci/hr , irradiation time t = 1hr
acitivity after 1 hr = 10(1-exp(-1.05e-4) ) = 1.05e-3 Ci
2. 2 gms solution Ao = 2Ci/hr ; irradiation time t = 5hr
acitivity after 2 hrs = 2(1-exp(-5.25e-4) ) = 1.05e-3 Ci
3. 1 gm solution, Ao = 1Ci/hr ; irradiation time t = 10hr
acitivity after 10 hrs = 1(1-exp(-1.05e-3) ) =1.05e-3 Ci
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