Question

A specific enzyme exhibits substrate inhibition. Why would it be quite possible to increase the reaction...

A specific enzyme exhibits substrate inhibition. Why would it be quite possible to increase the reaction rate by immobilizing the enzyme in a porous spherical particle compared to using the free enzyme in solution? Explain.

Homework Answers

Answer #1

In substrate inhibition there is a progressive decrease in activity at high substrate concentrations. If substrate concentrations are high, then using free enzyme in solution will inhibit the reaction rate. But, if this enzyme is immobalized, then it will not decrease the rate.

Think this type of enzyme as a poisonous catalyst. Its free presence will decrease the reaction rate.

So, it is possible to increase the reaction rate by immobilizing the enzyme in a porous spherical particle compared to using the free enzyme in solution

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