Question

A drug is ordered 100 mg/㎡ PO BID. How many milliliters will patient receive if her BSA is 1.80 m2 and the concentration of the solution is 100 mg/5mL?

For a client with diarrhea the recommended dosage of neomycin sulfate is 50mg/kg po in 4 divided doses for 2-3 days. If an order for 80 kg client with diarrhea is neomycin sulfate 1g po did for 3 days, is the order safe?

Answer 1

1. Given data

Desired dose ( ordered) = 100 mg/㎡

So 100 x 1.8 = 180 mg

BSA = 1.80 ㎡

Concentration of the solution =100 mg/5mL

The formula for dosage calculation is

Desired dose x volume = dose to be given

Available dose

180 mg x 5 mL = 9 mL

100 mg

The patient will receive 9 mL per dose.

2. Given data

Recommend dosage of neomycin= 50 mg/ kg / day for 3 days.

Patient weight= 80 kg

Dose to be given for patient = 50 x 80 = 4000 mg / day or 4 g / day

The patient can take 4g / day . So it is safe to give 1 gm po for 3 days.