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Is it true? Compartmental modeling of PET data typically uses measurements over time of 1) PET...

Is it true? Compartmental modeling of PET data typically uses measurements over time of 1) PET images of the target tissue and 2) concentrations of unchanged parent radioligand in plasma.

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The physiological system of dynamic processes in the tissue of interest is decomposed into a number of compartments, which interact with each other. Compartmental model is a basic idea to analyze dynamic PET data. The main principal behind the compartmental model is to categorizes the techniques and approaches for the compartmental model according to various aspects: model design, experimental design, invasiveness, and mathematical solution. We calculated VT using compartmental modeling with serial measurements of unchanged parent radioligand in arterial plasma and radioactivity in the brain. So the above given statement is true.

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