The primary health care provider ordered 100 mg of ampicillin orally q6h for a child who weighs 6 kg. Ampicillin is available in a concentration of 25 mg per 1 mL. The following 4 questions (a, b, c, and d) refer to this prescription.
Lexicomp 06/12/20 Reference: Oral: 50 to 100 mg per kg per day divided every 6 hours; maximum daily dose: 2,000 mg per day.
a) Calculate the safe daily dose range for this child
b) Calculate the safe dose range for this child
c) Is the above calculated dose safe for this child? Why?
d) What volume of ampicillin should the nurse prepare for a single dose?
a)Safe daily dose for this child.
Weight of the child = 6kg.
Recommended daily dose for this child = 50 to 100 mg/kg/day.
So
Safe dose for this child = 50 *6 to 100 *6
= 300 mg to 600 mg per day
b) Safe dose range for this child.
Safe daily dose range = 300 mg to 600 mg per day divided every 6 hrs.
Every 6 hr is 4 times a day.
So
Safe dose range = 300/4 to 600/4
= 75 mg to 150 mg.
c) Safe dose range is between 75 mg to 150 mg
per dose.
So, Ordered dose (100mg) is SAFE for this child.
d) Volume of drug required.
Volume (ml) = Desired dose/Dose in hand *Quantity.
Here
Desired dose = 100 mg.
Dose in hand = 25 mg.
Quantity = 1 ml
As per above formula
Volume (ml) = 100/25 * 1
= 4 * 1
= 4 ml.
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