Question

The assignment: ACE-I are known to be renoprotective (protect the kidney) Is BB renoprotective ??? YES or NO and WHY (ONLY 3 lines) Is CCB renoprotective ?? YES or NO and WHY (only 3 lines)

Answer 1

1) Yes

As compared to other antihypertensive agents, except RA system blockers, it has been confirmed that there are no demerits to using beta-blockers for renal protection. In addition, vasodilatory beta-blockers may also have beneficial renal-protective effects.

2) No

Calcium channel blockers (CCBs) are known to have potent antihypertensive effects and are considered the main candidates in combination treatment with ACEIs or ARBs in hypertensive patients with CKD.

However, evidence of the renoprotective effect of various types of CCBs is inconsistent. This inconsistency might be due to the different specificity of each CCB for different calcium channels.