In the superficial blood vessels, nasal swelling happened in the nasal mucosa was mainly caused by vasoconstriction. Decongestants are sympathomimetic agents (alpha-adrenergic agonists) that can reduce nasal passages swelling and it can opens clogged nasal passages. The oral decongestant can reduce the airflow resistance by decreasing the nasal mucosa volume.
The people with hypertension, hyperthyroidism, diabetes mellitus, cardiac disease, increased intraocular pressure or prostatic disease before taking a decongestant they should remember to read the drug label carefully because of many decongestants can be purchased over the counter (overdose problems). These drugs can directly affect the CNS and causes depression, convulsion and hallucination.
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