Question

A 64-year-old man with a history of essential hypertension is meeting with his nurse practitioner (NP). The patient's NP suspects that which of the following explanation is most likely occurring and is contributing to the patient's elevated blood pressure?

Question options:

	The patient's medications include endothelin-1 receptor antagonist.
	The patient's medications include synthetic ANP.
	The conversion of angiotensinogen I to angiotensin II in his kidneys causes increases in blood pressure and sodium reabsorption.
	The conversion of angiotensin I to angiotensin II in his lungs causes increases in blood pressure and sodium reabsorption.
	A and B

Answer 1

The explanation for elevated blood pressure of the patient may be

If the patient medication included endothelin -1 receptor antagonist it decreases blood pressure

Because endothelin causes vasoconstriction in lungs which increases blood pressure as we are using antagonist it decreases BP and it's not related to systemic hypertension

If patient medication includes synthetic anp it decreases blood pressure by causing natriuresis and diuresis and decreases BP

Conversion of angiotensinogen to angiotensin 1 with help of renin in kidney

Conversion of angiotensin 1to angiotensin ii occurs in lungs which increases blood pressure by

Increases aldosterone secretion

Sodium and fluid retention

Stimulates Muscle hypertrophy and fibrosis in heart

Vasoconstriction of blood vessels

This is the reason for the elevated blood pressure in the patient