Question

a. Bella, a 30-year old female, has a BMI of 32 kg/m2 . Given her obesity, her doctor prescribes Contrave, and recommends exercising. She starts her pharmacotherapy, and joins a gym. Explain how Contrave will pharmacologically aid her weight loss.

b. At her first session, Bella trips while jumping rope and falls on her knee. She has some codeine available and starts taking it as an analgesic. The codeine does not alleviate her pain as well as it used to though. Explain why codeine did not elicit its analgesic effect properly.

Answer 1

Ans)a) Constrave is a prescription-only, FDA-approved weight-loss pill believed to work on two areas of your brain—the hunger center and the reward system—to reduce hunger and help control cravings. Contrave contains two medicines, bupropion and naltrexone.

b)Codeine is an opiate.

- Codeine did not elicit its analgesic effect as:

Risk of opioid overdose- Do not take large amounts of opioids, including opioid-containing medicines, such as heroin or prescription pain pills, to try to overcome the opioid-blocking effects of naltrexone.
Sudden opioid withdrawal- Do not use any type of opioid for at least 7 to 10 days before starting Contrave.