A patient with schizophrenia will have alterations in their dorsolateral prefrontal cortex. The APRN would expect it to be described as:
stimulated |
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absent |
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hyperactive |
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hypoactive |
Hypoactive
Schizophrenia is a condition associated with structural and functional changes in a variety of brain areas. The key brain systems that are impacted by Schizophrenia include regions of medial temporal lobe and prefrontal temporal lobe. These regions are involved in declarative and working memory of a person. The dorsolateral prefrontal cortex is involved in greater cognitive functions such as switching attention, maintaining abstract rules and inhibiting unnecessary responses. Schizophrenia lead to decreased dorsolateral prefrontal cortex activation. Hypo-activity of the dorsolateral prefrontal cortex is greatly linked to the inhibitory control of action in patients with schizophrenia. Hence, the APRN will describe it as hypoactive response of the dorsolateral prefrontal cortex.
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