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Give at least five markers of differentiation between acute and chronic ITP

Give at least five markers of differentiation between acute and chronic ITP

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Idiopathic Thrombocytopenic Purpura (ITP) is a bleeding disorder which is caused by an abnormally low level of platelets in the patient's blood.

subject acute ITP chronic ITP
age childhood adults
bleeding sudden insidious
Degree of thrombocytopenia severe mild to moderate
duration limited (3-6 weeks) years
Pathogenesis Auto antibody binds to
platelet. Platelet destruction
in peripheral blood by
splenic macrophages.		 Specific
antibody(igG) binds to
specific platelet glycoprotein. Peripheral platelet destruction
and dysfunction.
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