Question

1. How is amlodipine metabolized?
2. What are the side effects of amlodipine?
3. What patient teaching will you provide when prescribing amiodarone?
4. What are the drug interactions with digoxin?
5. What is the purpose of a thyroid panel with amiodarone ?
6. What is nitrate tolerance?
7. What are the contraindications to therapy with Coumadin?
8. What classes of medications are used in the treatment of congestive heart failure?

Answer 1

Answer: Near about 90% of the amlodipine with the help of the hepatic breakdown gets converted in to metabolites which are inactive. Through which the 60% of the metabolites gets excreted through the urine whereas 10% present as the active compound.

The side effects of the amlodipine are:

• Headache
• Swelling/ edema
• Dizziness
• Palpitations
• Nausea
• Flushing.

The patient teaching will you provide when prescribing amiodarone includes as the drug should be taken as directed. Avoid the grape juice with the medication. There should be sufficient gap in the case of two dose.

Amlodipine drug does not have any drug interactions with the digoxin.