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Analyzed the relationship between Estradiol and osteoporosis

Analyzed the relationship between Estradiol and osteoporosis

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Answer #1

Menopause predisposes women to osteoporosis due to declining estrogen levels,This results in a decrease in bone mineral density(BMS) and an increase in fractures.

Estrogen is a sex harmone that is essential to female bone heath because it romotes the activity of osteoblasts,Which are cells that produce bone.

Estrogen deficiency can lead to excessive bone resorption accompained by inadequate bone formation.Osteoblasts,osteocytes,and osteoclasts all espress affects bones indirectly through cytokines and local growth factors.The estrogen replete state may enhance osteoclast apoptosis via increased production of transforming growth factor-beta.

Hence estrogens are given to reduce osteoporosis.

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