Question

Glycogen metabolism is regulated differently in the liver than in skeletal muscle. Explain the differences in...

Glycogen metabolism is regulated differently in the liver than in skeletal muscle. Explain the differences in regulation and why these differences are necessary based on the functions of glycogen in liver and skeletal muscle.

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Answer #1

GLYCOGEN METABOLISM IN LIVER:-
-glycogen metabolism in the liver mainly controlled by the concentration of phorphorylase alpha.
-The formation of phosphorylase alpha is stimulated by cAMP and by glycogen.
-The inactivation of glycogen synthetase is stimulated by cAMP, an elevated concentration of which puts a double lock on glycogen synthetase by activating phosphorylase alpha.

FUNCTIONS OF GLYCOGEN IN LIVER AND SKELETAL MUSCLE:-
- Glycogen functions in muscles as for energy source.
- In liver it is long-term energy reserves, in the form of triglyceride.

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