A patient comes to your office and complains of pain in their joints. The pain is constant regardless of movement, but it comes and goes over time. They say their initial symptoms were excruciating pain and swelling in the big toe, and they are having trouble walking when the pain flares up. The patient has no history of fractures or joint damage and rheumatoid factor tests were in the normal range. How do you proceed? What do the symptoms suggest? On the basis of what you have learned about the process of excretion, what is likely happening to the patient?
By the patient complaint it show that the patient should be sent for the blood examination,and other tests like white blood cell count and electrolytes and kidney function test and electrocyte sedimentation rate and x rays , the symptoms suggest that it may be gout, in gout it is seen that there is recurrent attack of acute inflammatory arthritis and mostly the big toe is affected, the causes are relatively high levels of uric acid in the blood, normally the uric acid does not accumulate they get excreted by urine and GIT, but in patient with gout the renal excretion of uric acid is decreased and get accumulates in the blood.
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