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What are controlled drug release systems and give two examples.

What are controlled drug release systems and give two examples.

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Answer #1

Control drug release system will deliver the drug at a predetermined rate locally or systemically,for a specified period of time.

ADVANTAGE:increase the safety margin of high potency drug

: fluctuation in steady state level is reduced

DISADVANTAGE:decrease systemic availability

:retrieval of drug is difficult in toxicity

EXAMPLES:1.Rate programmed drug delivary system(ocuserts,progestasert IUD.

2.Activation modulated drug delivary system

summary:They release drug at a predetermined rate,for locally or systemically,for a specified period of time.Eg:ocuserts,progestasert

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