Question

The quinolone antimicrobials function by The quinolone antimicrobials function by inhibiting DNA replication. inhibiting protein synthesis....

The quinolone antimicrobials function by

The quinolone antimicrobials function by

inhibiting DNA replication.
inhibiting protein synthesis.
inhibiting a metabolic pathway.
disrupting cytoplasmic membranes.
inhibiting cell wall synthesis.

Homework Answers

Answer #1

Ans) Inhibiting DNA replication

Explaination:

- Quinolone. : A class of synthetic antibacterial drugs that are derivatives of hydroxylated quinolines and inhibit the replication of bacterial DNA.

- They are used against gram negative organisms.

- The precise mode of action of the quinolones is not clear but predominant mode of action is by inhibition of DNA replication.

- Quinolones bind to the topoisomerase IV/DNA gyrase–DNA complexes and this results in the inhibition of DNA replication.

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