The quinolone antimicrobials function by
The quinolone antimicrobials function by
inhibiting DNA replication. |
inhibiting protein synthesis. |
inhibiting a metabolic pathway. |
disrupting cytoplasmic membranes. |
inhibiting cell wall synthesis. |
Ans) Inhibiting DNA replication
Explaination:
- Quinolone. : A class of synthetic antibacterial drugs that are derivatives of hydroxylated quinolines and inhibit the replication of bacterial DNA.
- They are used against gram negative organisms.
- The precise mode of action of the quinolones is not clear but predominant mode of action is by inhibition of DNA replication.
- Quinolones bind to the topoisomerase IV/DNA gyrase–DNA complexes and this results in the inhibition of DNA replication.
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