In your own words what do you know about Artificial Surfactant Replacement for premature infants?
Ans) Artificial Surfactant Replacement is a synthetic Surfactant (Lucinactant) that contains 21 amino acids peptide which mimics SP-B activity which prevents & treats RDS in premature infants.
- As Respiratory failure secondary to surfactant deficiency is a major cause of morbidity and mortality in premature infants.
- Surfactant therapy reduces the incidences of premature infants mortality as it helps in coating on the inside lining of the alveoli which makes it easier for the alveoli to expand during breathing. It also prevents the alveoli from collapsing and sticking together when air leaves the lungs completely.
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