Question

When blood sugar levels are low, this pancreatic hormone initiates glycogenolysis (i.e., glycogen breakdown)

Group of answer choices

insulin

ghrelin

IGF1

glucagon

Answer 1

Correct option is glucagon . Glucagon is peptide hormone secreted from alpha cells of pancreatic islets of Langerhans .

Hypoglycemia is physiologicall most secretory stimulus and best known action of glucagon is to stimulate glucose production in the iver and there by maintain adequate plasma glucose concentration.

NOT OTHERS WHY.

Insulin: . A key inhibitor of hepatic glucose production ,has effect on both glycogenolysis and gluconeogenesis .

Ghrelin is not a pancreatic hormone , its a central activity , ghrelin is involved in regulation of pancreatic development and physiology. Even it helpp in glycogenolysis but its not secreted from pancreas.

IGF-1( insulin growth factor ) : insulin and IGF-1 responsible for glycogen synthesis not glycogenolysis .

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