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When would the use of a randomised controlled trial be inappropriate? Give a public health example...

When would the use of a randomised controlled trial be inappropriate? Give a public health example and outline the reasons why conclusion randomised control trial would not be appropriate in this context.

There is not Public health option there so I selected Nursing

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Answer #1

The use of a randomized controlled trial would be inappropriate in situations in which we have heterogeneous populations and for complex phenomena because the conclusions of an RCT may not necessarily be valid
for each individual patient. One of the recognized problems of the RCT is its limited external validity. It may not always be possible to generalize the results of an RCT to the broader community, because screened volunteers for RCT 's are often good prognosis patients, in contrast to the general population (Grimes and Schultz, 2002). For example, if we are discovering a treatment and population of the human subject is not diverse then we may not generalize our finding for the patients globally.    

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