Question

share with your colleagues a case that presented to you in your practicum (or a personal experience). Describe how the skin disorder developed and what treatment was prescribed. Explain the cause of the skin disorder (bacterial, fungal, etc.), but focus on the treatment.

Include pharmacodynamics, pharmacokinetics, and pharmacotherapeutics of the medication prescribed (you may have to use an additional resource like Lexicomp, UpToDate, or Epocrates). Don’t forget monitoring and patient education.

Answer 1

The patient had seborrheic dermatitis. The patient had rash and was scaling which looked like dandruff in the scalp. The patient was treated with ketoconazole. The cause is exactly not known but it may be due to increased sebum production which leads to increased growth of normal skin yeast. The causative agent is fungi pityrosporum or malassezia.
Ketoconazole is used for fungal infections. It is an imidazole antimycotic. It bonds with the cytochrome and thus inhibits the biosynthesis of register and alters the permeability of fungal cell membranes. It inhibits mixed fiction oxidases, enzymes responsible for catabolism of prednisolone. It binds with the glucocorticoid receptor and acts as an antagonist.