Question

1.The ascending dose schedule of ropinirole (REQUIP) in the treatment of Parkinson’s disease is:

Week 1: 0.25 mg three times a day

Week 2: 0.5 mg three times a day

Week 3: 0.75 mg three times a day

Week 4: 1 mg three times a day

How many 0.25-mg tablets would provide the 4 weeks of treatment?

Answer 1

Answer:- 210 tablet
Explanation- total dose of four weeks in milligrams is -
Week 1 :- 0.25 mg × 3 times × 7 days = 5.25 mg
Week 2 :- 0.5 mg × 3 times × 7 days = 10.5 mg
Week 3 :- 0.75 mg × 3 times × 7 days = 15.75 mg
Weeek 4 :- 1 mg × 3 times × 7 days= 21 mg

Total dose of 4 weeks :-
5.25+ 10.5+15.75+21 = 52.5 mg
=> 1 tablet = 0.25 mg
= No. of tablet in 52.5 mg:-
         = 52.5/0.25
         = 210 tablet. Answer