Question

# Calculate the following corrected reticulocyte count which was performed using the Miller disc method. The patient...

Calculate the following corrected reticulocyte count which was performed using
the Miller disc method. The patient is an adult male. Show calculation.
# reticulocytes counted in larger square: 26
# RBCs (all cells) in smaller square: 111

Solution,

Formula to calculate corrected reticilocyte index in Miller disc method is as follows

= total reticulocyte in big square×100/total RBC in small square ×9

Here total reticulocyte in big square=26

RBC in smaller square=111.

= 26×100/111×9

=2600/999

=2.6

Corrected reticulocye count=2.6.

Corrected reticulocyte count is also known as reticulocyte index.

Corrected reticulocyte count is calculated based on normal hematocrit of 45%

In states of anemia, the reticulocyte percentage is not a true reflection of reticulocyte production. A correction factor must be used so as not to overestimate marrow production, because each reticulocyte is released into whole blood containing few RBC s-thus relatively increasing the percentage.

Average normal hematocrit for male is 45% and 42%

Corrected retic count is calculated by using formula,

=retic%×patients hematocrit%/average normal hematocrit.

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