Question

Calculate the following corrected reticulocyte count which was performed using
the Miller disc method. The patient is an adult male. Show calculation.
# reticulocytes counted in larger square: 26
# RBCs (all cells) in smaller square: 111

Answer 1

Solution,

Formula to calculate corrected reticilocyte index in Miller disc method is as follows

= total reticulocyte in big square×100/total RBC in small square ×9

Here total reticulocyte in big square=26

RBC in smaller square=111.

= 26×100/111×9

=2600/999

=2.6

Corrected reticulocye count=2.6.

Corrected reticulocyte count is also known as reticulocyte index.

Corrected reticulocyte count is calculated based on normal hematocrit of 45%

In states of anemia, the reticulocyte percentage is not a true reflection of reticulocyte production. A correction factor must be used so as not to overestimate marrow production, because each reticulocyte is released into whole blood containing few RBC s-thus relatively increasing the percentage.

Average normal hematocrit for male is 45% and 42%

Corrected retic count is calculated by using formula,

=retic%×patients hematocrit%/average normal hematocrit.