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A patient receiving morphine has an order for naloxone (Narcan) PRN. Why is the naloxone ordered?...

A patient receiving morphine has an order for naloxone (Narcan) PRN. Why is the naloxone ordered? What are the indications for using this drug? Compare and contrast naloxone with other narcotic antagonists.

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Answer #1

Naloxone is a narcotic antagonist that means it will reverse the effect of narcotic or opioid drug. So for the patient receiving morphine, the chances of morphine overdose is high. Thus, Naloxone is ordered to reverse the action of morphine overdose or side effects of morphine.

Indications for Naloxone :

  • used to reverse the effect of narcotic/opioid medications.
  • Treat opioid overdosage.
  • To diagnose use of opioid overdosage.

Other Narcotic antagonists:

  • Naltrexone
  • Nalmefene

The other narcotic antagonists has partial agonist effects compared to Naloxone.

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