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-Is it possible to prepare CRYO and FFP from the same unit of whole blood? Explain...

-Is it possible to prepare CRYO and FFP from the same unit of whole blood? Explain

-A nonbleeding adult of average height and weight with chronic anemia is transfused with 2 units of RBCs. The pretransfusion hemoglobin is 7.0 g/dL.

  1. What is the expected posttransfusion hemoglobin?
  2. List several potential reasons for a failure of the patient’s hemoglobin to increase after transfusion.
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Answer #1

Ans) Cryoprecipitated Antihemophilic Factor is more commonly known as cryoprecipitate, or simply cryo. Cryoprecipitate can only be made from Fresh Frozen Plasma (FFP), which has been removed from whole blood and frozen within eight hours of being collected. A single unit of cryo typically has a volume between 10 to 15 mL.

- Each unit of packed red blood cells (PRBCs) is expected to raise circulating hemoglobin (HGB) by approximately 1 g/dL. So PRBCs will raise 2g/dL.

- Diseases and conditions that cause your body to produce fewer red blood cells than normal include: Aplastic anemia, Cancer. Certain medications, such as anti-retroviral drugs for HIV infection and chemotherapy drugs for cancer and other conditions may not raise haemoglobin.

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