Question

In an autoimmune response, the healthy cells and tissues are destroyed, because the body’s ability to recognize itself is not working or malfunctioning. This results in the patient’s major systems malfunctioning and not able to function. The pathology involves T cells and autoantibodies that create the autoimmune diseases. An example is Type I diabetes. What happens in this situation?

Answer 1

PATHOPHYSIOLOGY OF TYPE-1 DIABETES:-
              -It is a chronic autoimmune disease associated with selective destruction of insulin- producing pancreatic ?-cells.
              -Presence of islet cell specific autoantibodies causes destruction of them.
              - Diagrammatic representation of mechanism:-