Question

A study was conducted to evaluate the relationship between artificial sweeteners and bladder cancer. 3,000 cases...

  1. A study was conducted to evaluate the relationship between artificial sweeteners and bladder cancer. 3,000 cases and 3,000 controls were enrolled in the study. Among the cases, 1293 had used artificial sweeteners in the past, while 1707 had never used artificial sweeteners. Of the controls, 855 had used sweeteners and 2145 had not.
    1. Which measure of association/comparison should we use to assess the strength of the relationship between the exposure and disease?
    2. Calculate the correct measure and show your work.
    3. How do we interpret this effect estimate?

Homework Answers

Answer #1

Answer:

Steps for calculation:

Relationship between artificial sweeteners and bladder cancer.

Amongst the cases, 1,293 had used artificial sweeteners in the past, while 1,707 had never used artificial sweeteners.

used AS = 1,293

Not used AS = 1,707

Among the controls, 855 had used sweeteners and 2,145 had not.

We can prepare a table from the above information,

Cases Controls

used AS a = 1,293 b = 855

Not used AS c = 1,707 d = 2,145

The odds of being a case may be calculated as

Therefore, we can conclude that a person having bladder cancer used artificial sweeteners was 1.90 times the odds that a person without bladder cancer used artificial sweeteners.

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