Answer : Highest safe amount of Digoxin should be administred at 10 am = 0.133 mg
Weight = 10 kg
Safe dose range for Digoxin is 0.02 to 0.04 mg/kg/day.
Step 1
Calculate the maximum dosage
From the given order 0.04 mg/kg/day is the maximum safe dosage
Maximum daily therapeutic dose = 0.04 mg × 10 kg
Maximum daily therapeutic dose = 0.4 mg
Step 2
To find out maximum dose to be given at 10 am
Medication frequency is q8h ( 10am, 6pm and 2 am)
So 0.4 mg should be given in three equal devided dose per day
ie each dose =
= 0.133 mg
Highest safe amount of Digoxin should be administred at 10 am = 0.133 mg
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