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How would coating a drug designed for oral administration in a relatively water-insoluble particle affect absorption?...

How would coating a drug designed for oral administration in a relatively water-insoluble particle affect absorption? Why?

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Answer #1

If we talk about the drug coating, yes it affects the absorption rate. There are many drugs which are designed and coated in they of their action and absorption.

Enteric coated: These are the tablets which are required to disintegrated in the intestine and not in the stomach. They are given coating which makes the tablets to pass the stomach as such but breaks in the alkaline medium.

Sustained action tablets are which after oral administration release the drug at a desired time and prolonged the effect of the medicament.

So, many drugs are being coated for their proper release and absorption also occurs accordingly.

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