Question

Please use the following information to answer questions 15 & 16.

Your 50-year-old female patient is prescribed hormone replacement (estrogen) therapy due to the effects of menopause

16. Normally, hormone replacement therapy decreases a woman’s chances of developing osteoporosis; however, your patient developed osteoporosis due to the hormone replacement therapy. Which of the following may have caused her osteoporosis?

a. Activated osteoblasts

b. Activated osteoclasts

c. An overactive thyroid

d. An underactive parathyroid

e. A & D

Answer 1

(a) Activated osteoblast is wrong

Because the estrogen level also increases the osteoblast lifespan .

● (b) Activated osteoclast is correct

Because estrogen in hormone therapy also inhibits the bone remodelling and affect the bone resorption. So the chance to cause osteoporosis

(C) an overactive thyroid is wrong

It may cause bone problem but it can repair with hormone therapy

(d) underactive parathyroid is wrong

An overactive parathyroid cause bone problems but particularly important bone targeted hormonal regulator is parathyroid hormone.

(e) is wrong