Differentiate between local and systemic inflammation Differentiate between passive and active acquired immunity Define where antibodies are produced Differentiate each type of hypersensitivity reaction (1-4) Differentiate between autoimmunity and alloimmunity What are risk factors for mercury poisoning? What are risk factors for lead poisoning? What is the pathophysiology of frostbite?
Local inflammation occurs in tissues and its effect is localised
In local inflammation macrophages secrete TNE in tissue,increase release in of plasma,phagocytes,lymphocytes and platlets adhsion ,phagocytosis of bacteria occurs resulting removel of infection
Systemic inflammation affect all vital systems in which macrophages release TNE in blood, edema ,decrease blood volume and collapsing vessels occur
There is depend upon severity of inflammation if severe intra vasculer coagulation occur and various organ demaged resulting death
Active acuired immunity is produced by body in which antigen is insert in to the body and body produce antibodies against antigen eg vaccination
But in passive acquired immunity already prepared antibody insert in to the body eg immunoglobins
Occ
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