Question

List cholinergic responses not normally caused when usual therapeutic doses of a muscarinic agonist are administered...

List cholinergic responses not normally caused when usual therapeutic doses of a muscarinic agonist are administered and why these effects do not occur.

Homework Answers

Answer #1

Answer: Muscarinic agonists produce contraction of the iris sphincter muscle, producing a small pupil diameter (miosis), and contraction of the ciliary muscle, which opens the trabecular network to allow increased outflow of aqueous humor through the canal of Schlemm.

  • Decrease intraoccular pressure by constricting pupil and contracting ciliary bodies of the eyes
  • Heart brake: lower heart rate, decrease output, lowers BP
  • Dilates blood vessels Skin, Viscera, Mucus Membranes (GI)
  • Increase tone and motility of GI smooth muscles
  • Increase peristalsis
  • Contraction of the detruser muscle bladder increase bladder pressure and relaxes trigone and bladder sphincter = urination
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