Question

Which of the following statements about the principles of drug therapy is INCORRECT?

(a) A narrow therapeutic index means the difference between a therapeutic dose and a toxic dose is small

(b) The onset of action of a drug is a measure of the time taken for the concentration to enter the therapeutic range

(c) The duration of action of a drug is a measure of the time period during which the concentration is within the therapeutic window

(d) When a patient is on maintenance therapy, the aim of the dosing regimen is to produce a steady-state concentration over time that is within the therapeutic window

(e) Graphs depicting concentration vs time pharmacokinetic profiles look similar irrespective of the route of administration of the drug

Answer 1

Correct answer:- (e) Graphs depicting concentration vs time pharmacokinetic profiles look similar irrespective of the route of administration of the drug.

Explanation:- Drug therapy includes-

a) A narrow therapeutic index means the difference between a therapeutic dose and a toxic dose is small

(b) The onset of action of a drug is a measure of the time taken for the concentration to enter the therapeutic range

(c) The duration of action of a drug is a measure of the time period during which the concentration is within the therapeutic window

(d) When a patient is on maintenance therapy, the aim of the dosing regimen is to produce a steady-state concentration over time that is within the therapeutic window.