A geriatric patient is likely to experience drug reactions more frequently than a younger patient. Which factor primarily account for this developmental variation?
a). Drugs crossing the placenta
b). Age-related physiologic changes
c). Increased drug metabolizing enzymes
d). Increased immune respone
A geriatric patient is an older person with impaired overall function. There is no set age, but he or she is usually more than 75 years old with chronic illness(es). Most age-related biologic functions peak before age 30 and gradually decline linearly thereafte. the decline. Ageing is associatedwith physiological changes that affect how medicines are handled, including alterations in volumes ofdrug distribution. So the age-related physiologic changes are can likely to experience drug reactions more frequently than a younger patient.
So the correct option: b). Age-related physiologic changes
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