Question

You are investigating the role of physical activity in the prevention of Alzheimer's disease and suggest that regular physical activity protects against development of Alzheimer's disease in the elderly. While presenting these data to your colleagues, someone asks if you have thought about confounders such as the APOE gene. This genetic profile could be confounding your interpretation of the data if it:

Answer 1

APOE tests are done to study the metabolism of fats in a patients body. It tells them if lipoproteins are working properly. If the tests show that APOE isn't functioning properlythen you cant use them for Alzheimers study. Their body genetically cant carry packaged cholesteroland other lipids through the bloodstream.

Before choosing patients you should implement APOE test to rule out patients that may have the genetic issues with the lipoproteins. By doing the APOE test you can interpret that patients who have no genetic issues with their lipoproteins are being helped with physical activity regarding Alzheimers disease.